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Angelman Syndrome What Parents Should Know

Angelman Syndrome: Key Information for Parents and Caregivers

Understanding the Basics

Angelman syndrome is a genetic disorder that mainly affects the nervous system and development. It is primarily caused by genetic changes in a gene located on chromosome 15. In most cases, neither parent has the condition, and the genetic change occurs randomly.

Recognize the Symptoms

Distinctive features and symptoms characterize Angelman syndrome. These may include intellectual disability, delayed development, speech difficulties, and a unique behavioral profile that often includes frequent laughter and hand-flapping movements.

Diagnosing the Condition

A healthcare professional may suspect Angelman syndrome based on the child's symptoms. Genetic testing can confirm the diagnosis.

Education and Awareness

For parents and caregivers of individuals with Angelman syndrome, education is crucial. Understanding the condition, its potential implications, and available therapies can support the child's development and well-being. It is also essential to raise awareness among others, fostering support and understanding.

Genetic Transmission

In rare cases, Angelman syndrome can be passed from an affected parent to a child through inherited genetic changes. However, this is not the typical mode of transmission.

Importance of Chromosome 15

The Angelman syndrome gene is located on chromosome 15. Certain genes on this chromosome are active, while others remain inactive. In individuals with Angelman syndrome, specific genes crucial for normal development may be inactive, leading to the distinctive characteristics associated with the condition.


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